NU643 2022 January Week 3 Discussion (dq1+dq2) Latest

NU643 Advance Psychopharmacology

Week 3 Discussion 

DQ1 Enzymes

Initial Post

By now, you have chosen your enzyme topic for this discussion forum.

Topic 1: CYP 1A2 enzyme

Topic 2: CYP 2D6 enzyme

Topic 3: CYP 3A4 enzyme

For this discussion, each student will create a four to five slide PowerPoint presentation including voice-over, that will be used to educate your fellow classmates on your chosen topic. Be creative in presenting your topic and include at least two references (in APA format) beyond Stahl for your information.

Each student is to create a PowerPoint for their topic and submit to this discussion forum when complete. Please answer the following questions in your presentation.

What is your enzyme?

Why is it important?

What does it do in the human body?

What are the common medications that inhibit the enzyme, including any substrates?

What are the important medication restrictions regarding this enzyme?

DQ2 Psychotropic Drugs

Overview

For this assignment, you will choose one psychotropic drug that is metabolized by CYP450 enzymes and complete the following steps:

Create a brief PowerPoint presentation, including voice-over, hypothesizing the outcome of prescribing your chosen drug in the presence of its CYP450 inhibitor and inducer.

Answer the following questions:

What are examples of drugs that will inhibit and induce the psychotropic drug you chose to study? What will happen, e.g., side effects, symptoms in the patient if the psychotropic drug was prescribed along with either its (1) inhibitor or (2) inducer?

For which CYP450 enzyme/s is it a substrate?

What are the pharmacokinetic considerations when prescribing this medication (absorption, distribution, elimination)? Dietary considerations? Dosing times

Initial Post

Once you have created your summary and presentation, submit under the appropriate discussion thread topic.