Which of the following options is the best way to punctuate

- Which of the following options is the best way to punctuate this sentence?

1- Microarray users acknowledge that an all-inclusive finger-prick test is unlikely to materialize anytime soon, but they have a more modest goal for their next decade (to streamline their search for meaning in a vast sea of data).

2- Microarray users acknowledge that an all-inclusive finger-prick test is unlikely to materialize anytime soon, but they have a more modest goal for their next decade: to streamline their search for meaning in a vast sea of data.

3- Microarray users acknowledge that an all-inclusive finger-prick test is unlikely to materialize anytime soon, but they have a more modest goal for their next decade; to streamline their search for meaning in a vast sea of data.

- Which of the following options is the best way to punctuate this sentence?

1- They fit a model only on a portion of the dataset; called the training set; and then test its discriminatory ability on the untouched data; called the validation or test set.

2- They fit a model only on a portion of the dataset (called the training set) and then test its discriminatory ability on the untouched data (called the validation or test set).

3- They fit a model only on a portion of the dataset—called the training set—and then test its discriminatory ability on the untouched data—called the validation or test set.

4- They fit a model only on a portion of the dataset: called the training set; and then test its discriminatory ability on the untouched data: called the validation or test set.

- Read this sentence: "This light detection changes the Phytochrome's conformation between a state under red light that binds directly to a phytochrome interacting factor (PIF) and a state under infrared light that doesn't bind to PIF." This sentence suffers from all of the following problems EXCEPT:

1- Unparallel sentence structure

2- Needless wordiness

3- Lack of clarity