Quiz 7 - What best describes the focus of population

Question # 00822417 Posted By: wildcraft Updated on: 04/09/2022 03:59 AM Due on: 04/09/2022
Subject Education Topic General Education Tutorials:
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Class 7 quiz 

Question 1 What best describes the focus of population genetics?

Evolutionary changes in population allele frequencies

Evolutionary changes in population genotype frequencies

Allele and genotype frequencies within populations

Allele and genotype differences between individuals

 

 

 

Question 2What two genetically-determinable quantities does the Hardy Weinberg equilibrium relate?

 

Phenotype prevalence within populations

Genotype and phenotype frequencies

Allele and phenotype frequencies

Allele and genotype frequencies

Question 3 If the frequency of alleles “a” and “A” within a population are 30% and 70% respectively, what are the the expected Hardy Weinberg frequencies of various possible genotypes?

aa = 9% AA = 49% aA = 42%

aa = 28% AA = 30% aA = 42%

aa = 9% AA = 42% aA = 49%

aa = 49% AA = 9% aA = 42%

Question 4 How might the Hardy Weinberg relationship be used to evaluate a new SNP genotyping technology using multiple individuals from a population?

If genotypes match the reference genome, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs.

If observed phenotypes follow Hardy Weinberg, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs.

If genotypes and allele frequencies follow Hardy Weinberg, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs.

None of the above

Question 5 What best describes the focus of Pharmacogenomics?

Relationships between metabolism of pharmaceuticals and genetic pathways.

Relationships between therapeutic effectiveness of pharmaceuticals and genomic makeup of individuals.

Pharmaceutical side effects, personalized medicine, and genetic testing of patients.

Genomics and genetics of disease-causing mutations and the search for effective medicine to remedy these.

Question 6 Why might a pharmaceutical company restrict the ethnicity of patients participating in a medical trial or, better yet, require patient genotype data (hint: population genetics of drug metabolizing enzymes, receptor isoforms, etc)?

To sample genetic variation and identify more adverse drug responses.

To increase potential genetic variation and (hopefully) obtain more clear-cut results.

To reduce potential genetic variation and (hopefully) obtain more clear-cut results.

There is no generally valid reason to do this.

Question 7 What best describes the "1000 genomes" project?

A project intended to demonstrate that 1000 genomes can sufficently represent human variation.

A long-runing project described as "A deep catalog of human genetic variation"

A project aimed at getting the cost of medical sequencing down to a managable level.

None of the above

Question 8 What is NOT true of "exome" sequencing as compared to whole genome sequencing?

Exome sequencing is cheaper.

All protein coding genes are covered.

Covers approximately 10% of the genome.

Can miss important genomic features (like regulatory regions, RNA-genes, etc).

short essay

Question 9 What is meant by “$1000 genome” and “personalized medicine”; In other words, how might readily available genetic information be used to provide better medical diagnostics and treatment?

Question 10 What are some current barriers slowing deployment of personalized medicine?

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