MN553 Full Course (wk 8,9 dq, seminar&practice; quiz,assignment) Latest 2017 July

MN553 Unit 1 Assignment Latest 2017 July

Assignment Directions

Choose a prescription drug that has a generic available. Choose three different types of pharmacies. Examples:

1. Large chain pharmacy such as Walgreens, CVS, Eckards, etc.

2. Grocery store associate pharmacy such as Publix, Krogers, etc.

3. Privately owned local pharmacy

4. Pharmacy associated with a “big box” store such as Target, Walmart, etc.

5. Online pharmacy (must be in the United States)

Do not use any drugs on the pharmacy’s four dollar or other special price list. If the pharmacy has a “club card” or other special way of getting lower cost, do not use this cost.

Compare the cash cost of the brand and the generic making sure that the dose (milligrams, micrograms, etc.) and number of pills are the same.

Example: Synthroid .05 milligrams and levothyroxine .05 milligrams, prescription for 30 pills.

For over-the-counter products, use identical products including formulation (liquid, capsules, etc.), dose (mgs per tablet, mgs per cc, etc.) and size of packaging (20 tablets in the box, 90cc fluid in the bottle, etc.). Try to avoid products that contain multiple ingredients like cold preparations as these are hard to compare due to differing quantities of ingredients within each product.

Example: Benadryl (brand) 25 mg per capsule, 25 capsules per bottle and diphenhydramine (generic) 25 mg per capsule, 25 capsules bottle.

	Cash Price at Pharmacy A	Cash Price at Pharmacy B	Cash Price at Pharmacy C
Brand name prescription drug
Generic of above prescription drug
Over-the-counter drug
Generic or store brand of the over-the-counter drug used above

MN553 Unit 3 Assignment Latest 2017 July

Topic: Pharmacotherapeutics of Gastrointestinal Disorders

For the diagnosis of gastroesophageal reflux disease (GERD), write a prescription for a medication used to treat GERD.

Be sure to indicate drug name, strength, amount per dose, route, frequency of dose, amount to dispense, allow generics, number of refills and any special instruction to the patient

Assignment Requirements:

Before finalizing your work, you should:

• be sure toread the Assignment description carefully (as displayed above);
• consult the Grading Rubric (under Course Resources) to make sure you have included everything necessary; and
• utilizespelling andgrammar check to minimize errors.

How to Submit:

Submit your Assignment to the unit 3 Assignment Dropbox before midnight on the last day of the unit.

When you are ready to submit your Assignment, select the unit dropbox then attach your file. Make sure to save a copy of the Assignment you submit.

MN553 Unit 4 Assignment Latest 2017 July

Topic: Respiratory Issues Complicated by Economic Disadvantage

A mother brings her 8-year-old child to the clinic, stating the child “just isn’t breathing right, doesn’t want to play, just lies on the couch — this happens all the time.”

The appearance of both mother and child is disheveled. The child’s wheezing can be heard across the room. When asked if the child is better at any certain time of the day, the mother responds, “It’s like this all the time and has been for the past year — we saw a doctor last year who diagnosed asthma but we don’t have any money for drugs or to come back to the clinic.”

Directions:

*****This Assignment may be submitted in a PowerPoint presentation with at least 10 slides or as an APA formatted paper of no more than five (5) pages excluding title page and references.

• Identify the resources currently available in your state to support this family in the care of this child, including assistance programs for costs of health care follow-up and pharmaceutical treatment agents.
• Create a communication plan for mother and child for both prescriptive and non-prescriptive drug therapies.

MN553 Unit 6 Assignment Latest 2017 July

Assignment Directions

Discussion: Mr. Smith brings his 4-year-old to your office with chief complaints of right ear pain, sneezing, mild cough, and low-grade fever of 100 degrees for the last 72 hours. Today, the child is alert, cooperative, and well hydrated. You note a mildly erythemic throat with no exudate, both ears mild pink tympanic membrane with good movement, lungs clear. You diagnose an acute upper respiratory infection, probably viral in nature. Mr. Smith is states that the family is planning a trip out of town starting tomorrow and would like an antibiotic just in case.

Create a communication plan for Mr. Smith and/or families for both prescriptive and non-prescriptive drug therapies. Describe what you would tell Mr. Smith and the child. Provide resources that Mr. Smith could access which would provide information concerning your decision.

Assignment Requirements:

*****This Assignment may be submitted in a PowerPoint presentation with at least 10 slides or as an APA formatted paper of no more than five (5) pages excluding title page and references.

Before finalizing your work, you should:

• be sure toread the Assignment description carefully (as displayed above);
• consult the Grading Rubric (under Course Resources) to make sure you have included everything necessary; and
• utilizespelling andgrammar check to minimize errors.

MN553 Unit 9 Assignment Latest 2017 July

Case Study: Prescribed Drugs with CAMs

A 35-year-old male, Mr. NX, presents to your clinic today with complaints of back pain and “just not feeling good.” Regarding his back, he states that his back pain is a chronic condition that he has suffered with for about the last 10 years. He has not suffered any specific injury to his back. He denies weakness of the lower extremities, denies bowel or bladder changes or dysfunction, and denies radiation of pain to the lower extremities and no numbness or tingling of the lower extremities. He describes the pain as a constant dull ache and tightness across the low back.

He states he started a workout program about 3 weeks ago. He states he is working out with a friend who is a body builder. He states his friend suggested taking Creatine to help build muscle and Coenzyme Q10 as an antioxidant so he started those medications at the same time he began working out. He states he also takes Kava Kava for his anxiety and garlic to help lower his blood pressure.

His historical diagnoses, currently under control, are:

Type II diabetes since age 27

High blood pressure

Recurrent DVTs

His prescribed medications include:

Glyburide 3 mg daily with breakfast

Lisinopril 20 mg daily

Coumadin 5 mg daily

Directions:

*****This Assignment may be submitted in a PowerPoint presentation with at least 10 slides or as an APA formatted paper of no more than five (5) pages excluding title page and references.

Based on the above case study, address each section of the Unit 9 Assignment template. Be sure to first view the Unit 9 Assignment Grading Rubric (found in the Grading Rubrics section under Course Resources) and use it to guide your completion.

1. Download the Unit 9 Assignment template or make a PowerPoint presentation.

2. Rename the downloaded template file as “FirstInitial+LastName_ MN553_Unit9.docx” (e.g., JDoe_MN553_Unit4.docx).

3. Review the Assignment grading rubric.

4. Complete the template, basing your responses on the case study above.

5. Support your arguments with appropriate evidence from the literature, citing and referencing in APA 6th edition style.

6. Upload your completed file to the unit 9 Assignment Dropbox. Please be sure to confirm that your file uploaded correctly.

MN553 Unit 8 Discussion Latest 2017 July

Unit 8 Discussion

Pharmacotherapeutics for Depression

Margo is a 49-year-old divorced woman who works as a bank teller. She tells her primary care provider (PCP) that she feels tired all the time and she is gaining weight because she has no interest in her usual exercise activities and has been overeating, not from appetite but out of boredom. She notices that she has difficulty falling asleep at night and awakens around 4 a.m. most mornings, without her alarm, and cannot go back to sleep even though she still feels tired. She finds little joy in her life but cannot pinpoint any particular concern. The PCP asks Angela to fill out a Beck’s Depression Scale, which indicated she has moderate depression.

Your first line of treatment leads you to prescribe citalopram for Margo that she is to take daily and return for follow-up in 6 weeks.

• Write that prescription.(Be sure to indicate drug name, strength, amount per dose, route, frequency of dose, amount to dispense, allow generics, and number of refills.)

• Provide Margo with written education regarding her prescription.(Include what she should expect when first taking the drug, appropriate activity warnings, when to expect improvement, side effects she may experience, and anything she should report to the provider). Write this is a narrative form as though you were talking to the patient.

MN553 Unit 9 Discussion Latest 2017 July

Unit 9 Discussion

Pharmacogenomics in Primary Care

Explain one of the following statements in your own words. Give an example of implications for you as the prescribing primary care provider.

1. Carbamazepine has a black box warning recommending testing for theHLA-B*1502 allele in patients with Asian ancestry prior to starting therapy.

2. Testing for CYP2D6 variants prior to starting tamoxifen for breast cancer.

3. A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body.

MN553 Unit 1 Seminar Quiz Latest 2017 July

Question 1 5 / 5 points

In what year did was the Durham-Humphrey Amendment enacted which stated that a physician must prescribe drugs and a pharmacist must dispense them?

Question options:

1932

1938

1952

1958

Question 2 5 / 5 points

All of the following are schedule II medications except?

Question options:

Ecstasy

Meperidine

Cocaine

Pentobarbital

Question 3 5 / 5 points

Which pregnancy category do medications fall under if animal studies have shown an adverse effect on the fetus, no adequate human studies, and that benefits may outweigh risks?

Question options:

Cat. X

Cat. A

Cat. B

Cat. C

Question 4 5 / 5 points

True or False: To be found negligent and responsible for harm resulting from your professional activities, courts generally require the presence of 4 conditions, to include duty, derelict, directly and damage?

Question options:

True

False

Question 5 5 / 5 points

True or False: Pharmacodynamics is the study of the body’s impact on the drug to include absorption, distribution, metabolism and excretion?

Question options:

True

False

MN553 Unit 2 Seminar Quiz Latest 2017 July

Question 1 5 / 5 points

All of the following are variables that affect drug actions except?

Question options:

Height

Weight

Age

Placebo response

Question 2 5 / 5 points

Which medication route has a 100% bioavailability?

Question options:

PO

IM

IV

SQ

Question 3 5 / 5 points

What must be present before a drug exerts its pharmacologic action on body cells?

Question options:

A specified amount of time since administration

The minimum effective concentration

Metabolism has been completed

The medication has been excreted by the kidneys

Question 4 5 / 5 points

True or False: Pharmacodynamics involves drug actions on target cells and the resulting alterations in cellular biochemical reactions?

Question options:

True

False

Question 5 5 / 5 points

True or False: In older adults increased total body water and lean body mass-fat soluble meds stay with the patient longer?

Question options:

True

False

MN553 Unit 3 Seminar Quiz Latest 2017 July

Question 1 5 / 5 points

True or False: Zollinger-Ellison Syndrome is the excessive secretion of gastric acid and a high incidence of ulcers. It is caused by gastrin-secreting tumors in pancreas, stomach or duodenum?

Question options:

True

False

Question 2 5 / 5 points

All of the following may cause Gastroesophageal Reflux Disease except?

Question options:

Alcohol

Chocolate

Beta adrenergic blockers

Anticonvulsants

Question 3 5 / 5 points

True or False: The treatment for Helicobacter Pylori requires a combination of two antimicrobials and a PPI or an H2RA?

Question options:

True

False

Question 4 5 / 5 points

All of the following are antiemetic herbal remedies except?

Question options:

Peppermint

Saw palmetto

Cayenne

Meadowsweet

Question 5 5 / 5 points

All of the following are causes of diarrhea except:

Question options:

Laxative abuse

Inflammatory bowel disease

Gastroesophageal reflux disease

Drug therapy

MN553 Unit 3 Quiz Latest 2017 July

Question 1 2 / 2 points

Jim presents with complaints of “heartburn” that is minimally relieved with Tums (calcium carbonate) and is diagnosed with gastroesophageal reflux disease (GERD). An appropriate first-step therapy would be:

Question options:

Omeprazole (Prilosec) twice a day

Ranitidine (Zantac) twice a day

Famotidine (Pepcid) once a day

Metoclopramide (Reglan) four times a day

Question 2 2 / 2 points

An elderly person has been prescribed lactulose for treatment of chronic constipation. Monitoring with long-term treatment would include:

Question options:

Electrolytes, including potassium and chloride

Bone mineral density for osteoporosis

Magnesium level

Liver function

Question 3 2 / 2 points

The next step in treatment when a patient has been on proton pump inhibitors twice daily for 12 weeks and not improving is:

Question options:

Add a prokinetic (metoclopramide)

Referral for endoscopy

Switch to another proton pump inhibitor

Add a cytoprotective drug

Question 4 2 / 2 points

If a patient with H. pylori-positive peptic ulcer disease fails first-line therapy, the second-line treatment is:

Question options:

Proton pump inhibitor bid plus metronidazole plus tetracycline plus bismuth subsalicylate for 14 days

Test H. pylori for resistance to common treatment regimens

Proton pump inhibitor plus clarithromycin plus amoxicillin for 14 days

Proton pump inhibitor and levofloxacin for 14 days

Question 5 2 / 2 points

Erika has been prescribed isotretinoin (Accutane) by her dermatologist and is presenting to her primary care provider with symptoms of sadness and depression. A Beck’s Depression Scale indicates she has mild to moderate depression. What would be the best care for her at this point?

Question options:

Prescribe a select serotonin reuptake inhibitor (SSRI) antidepressant

Refer her to a mental health therapist

Contact her dermatologist about discontinuing the isotretinoin

Reassure her that mood swings are normal and schedule follow up in a week

 

MN553 Unit 4 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Digoxin levels need to be monitored closely when the following medication is started:

Question options:

Loratadine

Diphenhydramine

Ipratropium

Albuterol

Question 2 1 / 1 point

When educating patients who are starting on inhaled corticosteroids, the provider should tell them that:

Question options:

They need to get any live vaccines before starting the medication.

Inhaled corticosteroids need to be used daily during asthma exacerbations to be effective.

Patients should rinse their mouths out after using the inhaled corticosteroid to prevent thrush.

They can triple the dose number of inhalations of medication during colds to prevent

needing systemic steroids.

Question 3 1 / 1 point

Second-generation antihistamines such as loratadine (Claritin) are prescribed for seasonal allergies because they are:

Question options:

More effective than first-generation antihistamines

Less sedating than the first-generation antihistamines

Prescription products, therefore are covered by insurance

Able to be taken with central nervous system (CNS) sedatives, such as alcohol

Question 4 1 / 1 point

Henry presents to clinic with a significantly swollen, painful great toe and is diagnosed with gout. Of the following, which would be the best treatment for Henry?

Question options:

High-dose colchicine

Low-dose colchicine

High-dose aspirin

Acetaminophen with codeine

Question 5 1 / 1 point

Patients whose total dose of prednisone will exceed 1 gram will most likely need a second prescription for:

Question options:

Metformin, a biguanide to prevent diabetes

Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease

Naproxen, an NSAID to treat joint pain

Furosemide, a diuretic to treat fluid retention

 

MN553 Unit 5 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Elderly patients who are started on levothyroxine for thyroid replacement should be monitored for:

Question options:

Excessive sedation

Tachycardia and angina

Weight gain

Cold intolerance

Question 2 1 / 1 point

Potentially fatal granulocytopenia has been associated with treatment of hyperthyroidism with propylthiouracil. Patients should be taught to report:

Question options:

Tinnitus and decreased salivation

Fever and sore throat

Hypocalcemia and osteoporosis

Laryngeal edema and difficulty swallowing

Question 3 1 / 1 point

Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:

Question options:

Substitutes for insulin usually secreted by the pancreas

Decreases glycogenolysis by the liver

Increases the release of insulin from beta cells

Decreases peripheral glucose utilization

Question 4 1 / 1 point

Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and symptoms of hypoglycemia include:

Question options:

“Fruity” breath odor and rapid respiration

Diarrhea, abdominal pain, weight loss, and hypertension

Dizziness, confusion, diaphoresis, and tachycardia

Easy bruising, palpitations, cardiac dysrhythmias, and coma

Question 5 1 / 1 point

Sulfonylureas may be added to a treatment regimen for type 2 diabetics when lifestyle modifications and metformin are insufficient to achieve target glucose levels. Sulfonylureas have been moved to Step 2 therapy because they:

Question options:

Increase endogenous insulin secretion

Have a significant risk for hypoglycemia

Address the insulin resistance found in type 2 diabetics

Improve insulin binding to receptors

 

MN553 Unit 5 Quiz Latest 2017 July

Question 1 2 / 2 points

When blood glucose levels are difficult to control in type 2 diabetes some form of insulin may be added to the treatment regimen to control blood glucose and limit complication risks. Which of the following statements is accurate based on research?

Question options:

Premixed insulin analogues are better at lowering HbA1C and have less risk for hypoglycemia.

Premixed insulin analogues and the newer premixed insulins are associated with more weight gain than the oral antidiabetic agents.

Newer premixed insulins are better at lowering HbA1C and postprandial glucose levels than long-acting insulins.

Patients who are not controlled on oral agents and have postprandial hyperglycemia can have neutral protamine Hagedorn insulin added at bedtime.

Question 2 2 / 2 points

Prior to prescribing metformin, the provider should:

Question options:

Draw a serum creatinine to assess renal function

Try the patient on insulin

Tell the patient to increase iodine intake

Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions

Question 3 2 / 2 points

Insulin preparations are divided into categories based on onset, duration, and intensity of action following subcutaneous injection. Which of the following insulin preparations has the shortest onset and duration of action?

Question options:

Lispro

Glulisine

Glargine

Detemir

Question 4 2 / 2 points

The drugs recommended for older adults with type 2 diabetes include:

Question options:

Second-generation sulfonylureas

Metformin

Pioglitazone

Third-generation sulfonylureas

Question 5 2 / 2 points

Women with an intact uterus should be treated with both estrogen and progestin due to:

Question options:

Increased risk for endometrial cancer if estrogen alone is used

Combination therapy provides the best relief of menopausal vasomotor symptoms

Reduced risk for colon cancer with combined therapy

Lower risk of developing blood clots with combined therapy

 

MN553 Unit 6 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Jonathan has been diagnosed with strep throat and needs a prescription for an antibiotic. He says the last time he had penicillin he developed a red, blotchy rash. An appropriate antibiotic to prescribe would be:

Question options:

Penicillin VK, because his rash does not sound like a serious rash

Amoxicillin

Cefadroxil (Duricef)

Azithromycin

Question 2 1 / 1 point

Nicholas has been diagnosed with type A influenza. Appropriate prescribing of oseltamivir (Tamiflu) would include:

Question options:

Starting oseltamivir within the first 48 hours of influenza symptoms

Advising the patient he can stop the oseltamivir when his symptoms resolve

Educating the patient that oseltamivir will cure influenza

Prophylactic treatment of all family members

Question 3 1 / 1 point

The drug of choice for treatment of primary or secondary syphilis is:

Question options:

Ceftriaxone IM

Benzathine penicillin G IM

Oral azithromycin

Oral ciprofloxacin

Question 4 1 / 1 point

When treating suspected gonorrhea in a nonpregnant patient, the patient should be concurrently treated for chlamydia with:

Question options:

Azithromycin 1 gram PO x 1

Amoxicillin 500 mg PO x 1

Ciprofloxacin 500 mg PO x 1

Penicillin G 2.4 million units IM x 1

Question 5 1 / 1 point

Lila is 24 weeks pregnant and has been diagnosed with tuberculosis (TB). Treatment regimens for a pregnant patient with TB would include:

Question options:

Streptomycin

Levofloxacin

Kanamycin

Pyridoxine

MN553 Unit 6 Quiz Latest 2017 July

Question 1 2 / 2 points

Pong-tai is a 12-month-old child who is being treated with amoxicillin for acute otitis media. His parents call the clinic and say he has developed diarrhea. The appropriate action would be to:

Question options:

Advise the parents that some diarrhea is normal with amoxicillin and recommend probiotics daily.

Change the antibiotic to one that is less of a gastrointestinal irritant.

Order stool cultures for suspected viral pathogens not treated by the amoxicillin.

Recommend increased fluids and fiber in his diet.

Question 2 2 / 2 points

To prevent further development of antibacterial resistance it is recommended that fluoroquinolones be reserved for treatment of:

Question options:

Urinary tract infections in young women

Upper respiratory infections in adults

Skin and soft tissue infections in adults

Community-acquired pneumonia in patients with comorbidities

Question 3 2 / 2 points

Treatment for suspected gonorrhea is:

Question options:

Ceftriaxone 250 mg IM x 1

Ceftriaxone 2 grams IM x 1

Ciprofloxacin 500 mg PO x 1

Doxycycline 100 mg bid x 7 days

Question 4 2 / 2 points

If a woman presents with recurrent vulvovaginal candidiasis she may be treated with:

Question options:

Weekly intravaginal butoconazole for 3 months

Fluconazole 150 mg PO daily x 7 doses then monthly for 6 months

Weekly fluconazole 150 mg PO x 6 months

Intravaginal tioconazole x 14 days

Question 5 2 / 2 points

Bilal is a 5-year-old patient who has been diagnosed with tuberculosis. His treatment would include:

Question options:

Pyridoxine

Ethambutol

Levofloxacin

Rifabutin

 

MN553 Unit 7 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Ray has been diagnosed with hypertension and an angiotensin-converting enzyme inhibitor is determined to be needed. Prior to prescribing this drug, the NP should assess for:

Question options:

Hypokalemia

Impotence

Decreased renal function

Inability to concentrate

Question 2 1 / 1 point

Which of the following create a higher risk for digoxin toxicity? Both the cause and the reason for it must be correct.

Question options:

Older adults because of reduced renal function

Administration of aldosterone antagonist diuretics because of decreased potassium levels

Taking an antacid for gastroesophageal reflux disease because it increases the absorption of digoxin

Doses between 0.25 and 0.5 mg/day

Question 3 1 / 1 point

Juanita had a deep vein thrombosis (DVT) and was on heparin in the hospital and was discharged on warfarin. She asks her primary care provider NP why she was getting both medications while in the hospital. The best response is to:

Question options:

Contact the hospitalist as this is not the normal guideline for prescribing these two medications and she may have had a more complicated case.

Explain that warfarin is often started while a patient is still on heparin because warfarin takes a few days to reach effectiveness.

Encourage the patient to contact the Customer Service department at the hospital as this was most likely a medication error during her admission.

Draw anticoagulation studies to make sure she does not have dangerously high bleeding times.

Question 4 1 / 1 point

Robert, age 51 years, has been told by his primary care provider (PCP) to take an aspirin a day. Why would this be recommended?

Question options:

He has arthritis and this will help with the inflammation and pain.

Aspirin has anti-platelet activity and prevents clots that cause heart attacks.

Aspirin acidifies the urine and he needs this for prostrate health.

He has a history of GI bleed, and one aspirin a day is a safe dosage.

Question 5 1 / 1 point

Education of patients who are taking warfarin includes discussing their diet. Instructions include:

Question options:

Avoiding all vitamin K-containing foods

Avoiding high-vitamin K-containing foods

Increasing intake of iron-containing foods

Making sure they eat 35 grams of fiber daily

 

MN553 Unit 8 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Charlie is a 65-year-old male who has been diagnosed with hypertension and benign prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension because it:

Question options:

Increases peripheral vasoconstriction

Decreases detrusor muscle contractility

Lowers supine blood pressure more than standing pressure

Relaxes smooth muscle in the bladder neck

Question 2 1 / 1 point

Which of the following adverse effects are less likely in a beta1-selective blocker?

Question options:

Dysrhythmias

Impaired insulin release

Reflex orthostatic changes

Decreased triglycerides and cholesterol

Question 3 1 / 1 point

Beta blockers have favorable effects on survival and disease progression in heart failure. Treatment should be initiated when the:

Question options:

Symptoms are severe

Patient has not responded to other therapies

Patient has concurrent hypertension

Left ventricular dysfunction is diagnosed

Question 4 1 / 1 point

You are treating a patient with a diagnosis of Alzheimer’s disease. The patient’s wife mentions difficulty with transportation to the clinic. Which medication is the best choice?

Question options:

Donepezil

Tacrine

Doxazosin

Verapamil

Question 5 1 / 1 point

Antonia is a 3-year-old child who has a history of status epilepticus. Along with her routine antiseizure medication, she should also have a home prescription for_________ to be used for an episode of status epilepticus.

Question options:

IV phenobarbital

Rectal diazepam (Diastat)

IV phenytoin (Dilantin)

Oral carbamazepine (Tegretol)

 

MN553 Unit 9 Practice Quiz Latest 2017 July

Question 1 1 / 1 point

Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:

Question options:

A need to monitor drugs metabolized by 2D6 for toxicity

Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors

Decreased conversion of codeine to morphine by CYP 2D6

The need for lowered dosages of drugs, such as beta blockers

Question 2 1 / 1 point

Rifampin is a nonspecific CYP450 inducer that may:

Question options:

Lead to toxic levels of rifampin and must be monitored closely

Cause toxic levels of drugs, such as oral contraceptives, when coadministered

Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic failure

Cause nonspecific changes in drug metabolism

Question 3 1 / 1 point

Inhibition of P-glycoprotein by a drug such as quinidine may lead to:

Question options:

Decreased therapeutic levels of quinidine

Increased therapeutic levels of quinidine

Decreased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and elimination

Increased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and elimination

Question 4 1 / 1 point

Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:

Question options:

Toxic levels of warfarin building up

Decreased response to warfarin

Increased risk for significant drug interactions with warfarin

Less risk of drug interactions with warfarin

Question 5 1 / 1 point

Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing:

Question options:

Erythromycin

Digoxin

Cetuximab

Rifampin