Maryville University NUR660 EXAM 2

1. Which medication has the SE of losing hair

1. Know the effects of atypical antipsychotics in non-psychotic mania. D/t which theory?
2. The pt is bipolar, and had a partial response to depakote and now is going to be augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non-psychotic mania may be due to "what is hypothesized".....
3. A pt has had some success with his current antidepression medication, has tried many different antidepressants, so you decide to augment with L-methyl-folate. What is the hypothesis behind L methyl Folate boosting the therapeutic efficacy of antidepressants...what is the MOA?

1. You have a pt that has been very depressed and has insomnia problems with concentrations, weight loss and SI. You start them on an AD and his symptoms have abated, however which of the following symptoms is the most likely to be residual following the successful tx of other symptoms....is it depression, insomnia, other issues or SI?
2. Which class of antidepressant have a lower incidence of sexual SE? What medication is used in the tx of BP/mania and is used in prophylaxis as well as antidepressant augmentation? Which medication is this?
3. What medication is a very potent CYP450 inhibitor and can dangerously elevate lamotrigine?
4. Which class of antidepressant has the worst discontinuation syndrome? "You have a female pt complaining of lactating and is not pregnant w/ no children. She has been taking risperidone. Which medication would you avoid if you were to switch her to another med?"
5. A pt is on Prozac and it has stopped working and has been on many other antidepressants and wants to try and MAOI now. How long do you need to stop Prozac before starting MAOI?

1. What neurotransmitter are affected by TCAs?

1. A 60 yo female with resistant depression, taking Paxil. However, she is having recurrent SI.  You're thinking of starting her on a MAOI...what neurotransmitters are affected to produce antidepressant effects of the med suggested?
2. What TCA should absolutely not be used in combination with any other MAOI?

1. Please know what is the most potent property of trazodone?
2. Please review w/d syndrome of abrupt d/c of a TCA, what does that result in?
3. You have a pt with rapid cycling bipolar disorder. What drug combination can you give together, and what is the combo that can NOT be given together. Choices:  Lithium and lurasidone, Lamictal and quetiapine carbamazepine and lurasidone, valproate and quetiapine?
4. What medication is safe to take with MAOI?
5. What are the two factors that are most useful for determining if a presenting depressive episode is unipolar or bipolar? What do you need for an effective interview?

1. T/F questions... Figure out which of those statements is false.

Does methylfenalate increase or decrease TCAs?

Does clozapine increase TCA A levels?

Does cigarette smoking decrease TCA levels?

Do TCA have adverse cardiac S/Es?

1. A 28 yr old woman presents with depression. She has been treated with manic episode before however is not taking medication. Whhat meds work the best to tx bipolar depression? review antipsychotics and mood stabilizers...

1. This a question about MAOI....the pt had three therapeutic trials of SSRIs w/o any success...so now you're considering an MAOI.  Which of the following is an appropriate switching strategy?