How are hot spots related to recombination frequency

Question # 00559636 Posted By: dr.tony Updated on: 07/11/2017 04:52 AM Due on: 07/11/2017
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1. How are hot spots related to recombination frequency?

2. What is PRDM9 and what DNA motif does it likely bind?

3. How does DNA sequence contribute to the occurrence of

hot spots?

4. Is it possible for PRDM9 alleles to have different influences

on different hot spots? Please explain.

5. Do DNA motifs such as CCNCCNTNNCCNC necessarily

indicate that a hot spot will be present? What other factors

may influence the presence of a hotspot?


Reference http://europepmc.org/articles/PMC3092422

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