Chapter 15 - Explain the two main features that characterize

Please Pick 2 question to answer and provide reference. 

Chapter 15 

1.Explain the two main features that characterize the third line of host defense mechanisms. 

2.Chronic lymphocytic leukemia (CLL) leads to the production of cancerous B cells, and treatment often involves bone marrow transplantation. Based upon your knowledge of lymphocyte development, explain how this procedure can lead to therapeutic effects in some patients. 

3.Recently, scientists have been experimenting with using IRA-B cells as a treatment for hospitalized patients in an attempt to prevent them from getting septic infections. Speculate on what the principle behind this might be. 

4.Provide an explanation to refute the following statement: Humans would never develop natural immunity to a novel biological agent created in a laboratory. 

5.   a.Explain how the anamnestic response is triggered by vaccination. b.Conduct additional research and discuss one current example illustrating how lack of herd immunity within a population has led to localized disease outbreaks in the United States.