All questions to be answered in great detail, if possible use chemdraw.
only answer this if you are 100% sure in what are doing.
I will attach the two papers for answering the questions too.
Papers needed to answer some questions:
(2004) Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors, Bioorganic
Medicinal Chemistry Letters, vol.
Biochemistry paper below:
(1998) Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl Diphosphate
Analogue Biochemistry, vol.