Papers needed to answer some questions: BMCL Li, Q. et al.
Question # 00085373
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Updated on: 07/27/2015 02:40 AM Due on: 08/26/2015
All questions to be answered in great detail, if possible use chemdraw. only answer this if you are 100% sure in what are doing. I will attach the two papers for answering the questions too.
Papers needed to answer some questions:
BMCL
Li, Q. et al. (2004) Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors, Bioorganic
Medicinal Chemistry Letters, vol. 14, pp. 536770.
Biochemistry paper below:
Strickland, L. et al. (1998) Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl Diphosphate
Analogue Biochemistry, vol. 37, pp. 1660111
BMCL
Li, Q. et al. (2004) Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors, Bioorganic
Medicinal Chemistry Letters, vol. 14, pp. 536770.
Biochemistry paper below:
Strickland, L. et al. (1998) Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl Diphosphate
Analogue Biochemistry, vol. 37, pp. 1660111
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Solution: Papers needed to answer some questions: BMCL Li, Q. et al.