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BCHM 551 - A patient with OTC deficiency has recurrent

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Subject: Biology
Due on: 07/11/2017
Posted On: 07/11/2017 06:55 AM

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  1. A patient with OTC deficiency has recurrent hyperammonemic events over a 3-month period despite reduced protein intake and increased doses of sodium benzoate and sodium phenylacetate. What are the factors that need to be considered as a cause of the hyperammonemia in this individual? (Consider the dynamic of nitrogen balance over this period.) What is the likely treatment?
  2. Describe the biochemical reason why deoxygenated hemoglobin S polymerizes? Apart from polymerization, what are the causes of the clinical manifestations in sickle cell disease?

Tags recurrent deficiency patient bchm period sodium biochemical reason deoxygenated treatment dynamic nitrogen balance likely hemoglobin polymerizes sickle cell disease manifestations clinical apart polymerization causes consider hyperammonemia despite reduced protein 3month events deficiency recurrent hyperammonemic

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